Male sex bias in placental dysfunction

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Re: Male sex bias in placental dysfunction

Post by alviarin » Mon Mar 19, 2012 02:15 pm

Interesting. Don't male babies tend to be bigger? I wonder if that could be a factor.

Though this doesn't really apply to me either since I'm a chronic hypertensive.

Male sex bias in placental dysfunction

Post by caryn » Mon Mar 19, 2012 09:43 am

In families with the absence of maternal chronic hypertension (cHTN; n = 70), the index case was 5.9 (95% CI 2.28-16.15; P <0.001) times more likely to be male and most (12/14) affected sibs of male index cases were male, while female index cases had no affected sibs. Our results confirm a male fetal sex preponderance in SPD. In a subgroup analysis of families without cHTN, a significant male bias was found to extend to sibs of index cases.

This is one that doesn't apply to me, because maternal family history of hypertension was excluded from the sample population. It says the rate of SPD - severe placental dysfunction - is way higher if you're carrying a boy.