by caryn » Sun Nov 13, 2011 09:37 am
Oh! And on that note here's *another* new study reporting the same thing:
http://www.ncbi.nlm.nih.gov/pubmed/21545366This study demonstrates that aPL perturb the secretion of trophoblast angiogenic factors. LMWH does not reverse this effect but exacerbates sFlt-1 secretion, a potent anti-angiogenic factor. These findings may help to explain why women with antiphospholipid syndrome, who are treated with heparin to prevent early pregnancy loss, remain at increased risk of developing late obstetrical complications, such as pre-eclampsia...Also, fish oil got ruled out a while ago:
http://www.ncbi.nlm.nih.gov/pubmed/18669736 Supplementation with fish oil, calcium, or vitamin C and E and the use of antihypertensives have been shown to be ineffective in the prevention of recurrent preeclampsia and are not recommended. and has the potential to worsen matters (in this study it made you almost *5 times* more likely to get it):
http://www.ncbi.nlm.nih.gov/pubmed/1648 ... stractPlusThat last is an example of why I always say to run supplements past your MFMs!
Anyway, I doubt thinning the blood per se will do anything. If blood thinners like heparin/Lovenox/LDA are doing anything at all (and a lot of MFMs would say at least LDA is not, given the data from randomized controlled trials) it's likely because of something else that they do too, and not just because they thin the blood.
Oh! And on that note here's *another* new study reporting the same thing: http://www.ncbi.nlm.nih.gov/pubmed/21545366
[i]This study demonstrates that aPL perturb the secretion of trophoblast angiogenic factors. LMWH does not reverse this effect but exacerbates sFlt-1 secretion, a potent anti-angiogenic factor. These findings may help to explain why women with antiphospholipid syndrome, who are treated with heparin to prevent early pregnancy loss, remain at increased risk of developing late obstetrical complications, such as pre-eclampsia...[/i]
Also, fish oil got ruled out a while ago: http://www.ncbi.nlm.nih.gov/pubmed/18669736
[i] Supplementation with fish oil, calcium, or vitamin C and E and the use of antihypertensives have been shown to be ineffective in the prevention of recurrent preeclampsia and are not recommended. [/i]
and has the potential to worsen matters (in this study it made you almost *5 times* more likely to get it): http://www.ncbi.nlm.nih.gov/pubmed/16487202?dopt=AbstractPlus
That last is an example of why I always say to run supplements past your MFMs!
Anyway, I doubt thinning the blood per se will do anything. If blood thinners like heparin/Lovenox/LDA are doing anything at all (and a lot of MFMs would say at least LDA is not, given the data from randomized controlled trials) it's likely because of something else that they do too, and not just because they thin the blood.