by laura (5139 Posts), Wed Jan 07, 2004 02:54 pm
I had heard that high levels of homocysteine during early pregnancy were correlated with higher incidences of severe preeclampsia, though I don't think that they thought it was a cause of PE, rather a marker. High Homocysteine levels are also associated with cardiovascular disease, but again, I wasn't clear on what it meant for us with PE, and what they could do about it- with a little further research, I found this info here correlating high homocysteine levels with thrombophilias and treated with folate. Maybe they threw that one test in there because they suspect that there's a clotting disorder somewhere, and they're exhausting all possible avenues.
Hyperhomocysteinemia. A frequent condition in the general population, hyperhomocysteinemia is also an important contributor to the overall risk of thrombotic disease. Although the exact mechanism for this is unclear, mild to moderate increases in homocysteine levels are associated with an increased relative risk of thrombosis (2.5). Dietary restriction of folate and vitamin B12 remains the most common cause.
In any event, I hope they find something! It always makes you feel better to have an area to target. HTH.
Allie 5-13-98 (35 weeks-pre-e)
Baby Camille 4-17-03 (36 weeks- htn and oligo)