Post Reply FAQ Members Login

Searching for information

This section is for discussions with other women who have probably been through the same signs/symptoms that you may be experiencing. Please note, we cannot offer medical advice and encourage members to discuss their concerns with their doctors. New members, come on in and introduce yourself!

Searching for information

Postby iansmom » Sat Jan 17, 2004 02:15 pm

by iansmom (254 Posts), Sat Jan 17, 2004 02:15 pm

I got my most recent lab work back. One reading was slightly elevated (VMA). This is something they check for a rare adrenal tumor - phaeochromocytoma. I, of course, have been scouring the internet for information. As you all know, that has created more confusion and few answers. One article actually said that in pregnant women it can present as preeclampsia and all preg women with pe should be screened for it. That was the only article I found that likned the two (no, I can't remember the site.) Apparently it is so rare that 50% of cases are diagnosed post mortem because nobody ever thinks to check for it. Anyway, do any of you have any knowledge of this? Also, the VMA screening seems to be the least reliable test. the Metanephrine levell in urine is a better screening tool. My OB is not very concerned b/c the level was so slightly elevated. She wants me to discuss it with my cardio on the 29th. It is responnsible for less than 1% of hypertension patients, so I guess it is a long shot, but I meet many of the criteria (young for high BP, severely high BP, heart palpitations, family history of thyroid disease, etc.) I see how people become hypochondriacs, everything I read screams "YOU GOT IT!" I am skeptical, though - just want to know if ya'll have heard of this.

Ian 12/26/01 - 26 weeks P/E & HELLP
#2 EDD July 15, 2004
iansmom
Registered User
 
Posts: 254
Joined: Tue Sep 02, 2003 10:07 am

Re : Searching for information

Postby sonja » Sat Jan 17, 2004 02:47 pm

by sonja (5658 Posts), Sat Jan 17, 2004 02:47 pm

I am sorry, I don't have any info for you, I just wanted to say that the internet can be a scary place to find info - I would call your docs office and see if they can refer you to some site for more info. I will be interested to read what you learn. Good luck to you.

Joy
Kira 3-16-02 37 1/2 weeks PE
#2 EDD 6-5-04 (according to ultrasound)
sonja
Forum Moderator
 
Posts: 5658
Joined: Mon Jan 05, 2004 02:00 pm

Re : Searching for information

Postby laura » Sat Jan 17, 2004 04:15 pm

by laura (5139 Posts), Sat Jan 17, 2004 04:15 pm

I was just intrigued by your question- of course, I've never heard of phaeochromocytoma or a VMA (other than the award show on MTV)- but you've presented a internet search challenge [:o)]

I found this in reference to VMA's:

At least three 24 hour urine collections are necessary as many patients with phaeochromocytoma have intermittently raised levels.

The ingestion of substances containing phenols such as coffee, bananas, and vanilla flavourings, or of drugs such as methyldopa which interfere centrally or peripherally with sympathetic function, is to be avoided in the 24 hours prior to collection.

Twice normal levels are generally considered diagnostic of phaeochromocytoma. Levels may be slightly elevated in essential hypertension.



here:
http://www.gpnotebook.co.uk/cache/604373012.htm

So, you'd need at least two more 24 hour urines before you could really even start worrying, make sure your diet doesn't include those pretty darned ubiquitous things, AND have twice normal levels. Hope this helps!


Laura-28
DH Jack-31
Allicia 5-13-98 (35 weeks-pre-e)
Camille 4-17-03 (36 weeks- htn and oligo)
http://www.babiesonline.com/babies/c/camilleandallie/
laura
Registered User
 
Posts: 5139
Joined: Tue Jan 28, 2003 12:17 pm
Location: Anchorage, AK

Re : Searching for information

Postby taras mom » Sun Jan 18, 2004 02:18 am

by taras mom (841 Posts), Sun Jan 18, 2004 02:18 am

FYI: VMA stands for vanillylmandelic acid. According to Stedman's, it's "the major urinary metabolite of adrenal and sympathetic catecholamines (e.g., from both epinephrine and norepinephrine)." Given that both epinephrine and norepinephrine are vasoconstrictors and that epinephrine also increases cardiac output, it makes sense that elevated VMA might be seen in hypertension. What VMA and pheochromocytoma mean for women with PE is a good stump-the-OB question. Interesting!

Carol (38)
DH Bill (40)
Tara Mairichi
12/7-12/9, 2002
The Mightiest Little Angel
taras mom
Registered User
 
Posts: 841
Joined: Thu May 01, 2003 01:30 am

Re : Searching for information

Postby laura » Sun Jan 18, 2004 01:56 pm

by laura (5139 Posts), Sun Jan 18, 2004 01:56 pm

Carol- You're every woman. You, and Chaka Khan, and Oprah. How do you know this stuff?

I had no idea epinephrine increased cardiac output... THAT'S why Dr. E uses atenolol? Ding! (light going on)

Laura-28
DH Jack-31
Allicia 5-13-98 (35 weeks-pre-e)
Camille 4-17-03 (36 weeks- htn and oligo)
http://www.babiesonline.com/babies/c/camilleandallie/
laura
Registered User
 
Posts: 5139
Joined: Tue Jan 28, 2003 12:17 pm
Location: Anchorage, AK

Re : Searching for information

Postby taras mom » Sun Jan 18, 2004 04:11 pm

by taras mom (841 Posts), Sun Jan 18, 2004 04:11 pm

Thanks, Laura! Can I get an indoor pool, a chef, and personal trainer now?[:D]

As an editor, I have a pretty decent reference library. Once I was in Barnes & Noble buying Dorland's Medical Dictionary. The clerk asked, "Are you a doctor?" I said, "No, but I play one on TV." How often do you get an opportunity like that?

Carol (38)
DH Bill (40)
Tara Mairichi
12/7-12/9, 2002
The Mightiest Little Angel
taras mom
Registered User
 
Posts: 841
Joined: Thu May 01, 2003 01:30 am

Re : Searching for information

Postby iansmom » Wed Jan 21, 2004 08:01 am

by iansmom (254 Posts), Wed Jan 21, 2004 08:01 am

Thanks for the input. I am confused by the effects of the methyldopa. I have seen that it DOES affect and that it DOES NOT affect it. I am not sure what to think, but my level was VERY low - nowhere near double normal. But, could that be the methyldopa's effect? We'll have to see!

Ian 12/26/01 - 26 weeks P/E & HELLP
#2 EDD July 15, 2004
iansmom
Registered User
 
Posts: 254
Joined: Tue Sep 02, 2003 10:07 am


Return to Ask the Experienced

Who is online

Users browsing this forum: No registered users and 1 guest

cron