I believe multiples raise risk of cholestasis as well as PE--I know someone else who had both, with a triplet pregnancy.
Because your BP rose before, your hypertension may be chronic, not gestational (the normal cutoff is 20 weeks, but I don't know if multiples changes that equation). Methyldopa is very well studied in pregnancy--it's actually FDA category B. I would think that if an association between methyldopa use and cholestasis existed it would have been reported by now.
Aliza - 01/05/2007 - Severe preeclampsia, emergency CS 37 weeks
Isaac - 09/26/2011 - controlled on 150mg Toprol, NO PE, 39 weeks!