New/Reply FAQ Members Login

Leukocyte activation in PE

The Preeclampsia Foundation does not necessarily endorse any research or news found in this forum, we just want to share what is out there. Please use your own discretion to evaluate any information you find here.

Leukocyte activation in PE

Postby caryn » Mon Apr 06, 2009 01:54 pm

Altered concentrations of sL-selectin and elastase confirmed leukocyte activation in preeclampsia. These leukocytes showed up-regulation of Nuclear Factor of Kappa light chain gene enhancer in B cells inhibitor (NFkappaB-1A) and cyclin-dependent kinase inhibitor (CDKN)-1A compared with normotensive pregnant women. Interleukin-1 Receptor Antagonist (IL-1RA) and tumor necrosis factor (TNF)-R1 were increased compared with those in non-pregnant controls. Monocyte-derived MP were elevated in preeclamptic patients compared with pregnant women. The numbers of cytotoxic T-cell-derived and granulocyte-derived MP were elevated compared with those of non-pregnant women...

http://www.ncbi.nlm.nih.gov/pubmed/19341385

So our immune systems are annoyed; measuring markers of immune activity shows elevations in preeclamptics.

Information provided on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disorder, or prescribing any medication. The Preeclampsia Foundation presents all data as is, without any warranty of any kind, express or implied, and is not liable for its accuracy, for mistakes or omissions of any kind, nor for any loss or damage caused by a user's reliance on information obtained on the site. Professional opinions on this condition vary greatly. The Preeclampsia Foundation endorses no one course of treatment or "cure".
User avatar
caryn
Forum Moderator
 
Posts: 10110
Joined: Fri Jun 25, 2004 06:36 am

Re : Leukocyte activation in PE

Postby karoliina » Tue Apr 07, 2009 08:36 am

So does this mean that the reason my leucocytes have been up in late pregnancy might be "just" because of PE?

Karoliina
karoliina
Registered User
 
Posts: 503
Joined: Tue Feb 03, 2009 02:56 am

Re : Leukocyte activation in PE

Postby goldielockslizzy » Tue Apr 07, 2009 11:07 pm

....I had high monocytes which are a type of leukocyte in my second pregnancy... I had mild PE this time. hmm.......
goldielockslizzy
Registered User
 
Posts: 15
Joined: Sun Feb 15, 2009 11:57 pm


Return to Announcements and Preeclampsia in the News

Who is online

Users browsing this forum: No registered users and 3 guests