Are tests for predicting PE good enough?

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Are tests for predicting PE good enough?

Postby caryn » Sun Jun 07, 2009 00:31 am

...No test had a high level of both sensitivity and specificity of greater than 90%. Where multiple studies were available, only BMI > 34, alpha-fetoprotein, fibronectin (cellular and total), and uterine artery Doppler (bilateral notching) measurements reached specificity above 90%. Only Doppler (any/unilateral notching, resistance index, and combinations) measurements were over 60% sensitive. Studies were of variable quality and most tests performed poorly. Further research should focus on tests which offer much higher levels of sensitivity than tests currently available...

http://www.ncbi.nlm.nih.gov/pubmed/19488883

So, the tests still suck. They're planning to focus on developing tests that *overselect* women at risk for preeclampsia, even though that means that some of the women who score a positive test won't develop PE, because a pregnancy monitored more closely for PE where it doesn't develop is very likely to have a better outcome than a pregnancy not monitored closely that *does* develop it.

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