These data demonstrate that chronic infusion of VEGF121 during late gestation restores glomerular filtration rate and endothelial function and reduces high blood pressure associated with placental ischemia. The present results suggest that VEGF121 may be a candidate molecule for management of preeclampsia and its related complications.
Same question here: what happens to placental perfusion? 'Cause it's all well and good if we come up with something that reverses the mother's symptoms, but that won't address the reason the placenta is raising her pressures in the first place... namely to pump more blood across the placenta into the baby! (Still, a start to therapy is a start to therapy.)
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