by caryn (10159 Posts), Sat May 08, 2010 04:44 pm
In this study, we showed that the reported decrease for SOD activity in PE may be attributed to SOD1 in absence of labor. Also, this is the first study characterizing specific SOD isoforms according to the mode of delivery. We demonstrated in PE that labor upregulates SOD1 in fetal membranes as well as SOD2 and SOD3 in the whole placenta...
So labor does some stuff to us that it doesn't do to normal pregnant women, and that doesn't happen to us if we don't go into labor. SOD stands for "superoxide dismutase", a tissue antioxidant. The researchers will take a look at this specific change in the chemicals produced by the placenta to see if it suggests a theraputic change in clinical practice might be possible.
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