These results suggest that circulating factors during pregnancy affect the cerebral endothelium to diminish EDHF and increase tone, an effect that may impact cerebrovascular resistance and control of blood flow in the maternal brain.
http://www.preeclampsia.org/pdf/oaprogress.pdf <--caution, .pdf file
So, eventually, it's research like this that will help figure out why preeclampsia patients start seizing. Something about our brain activity is disrupted as we get sicker, but only magnesium sulfate helps to reduce the frequency of the seizures. Regular seizure drugs don't work.
When samples of our blood are used to flood a dish of rat cerebral artery cells, those cells respond very differently from the response they have to blood from women whose pregnancies were proceeding normally. So one of the chemical proteins in our bloodstreams -- a "circulating factor" -- is also a signal to cerebral artery cells. (At least in rats. Likely in us too, though -- it's just that it's a lot harder to check in us than in rat cells.)
The researcher, Dr. Amburgey, also says, These experiments have been completed, and data analysis is ongoing. We hope to present this work at a national conference next year and plan on submitting a manuscript in the next few months. yay!
Information provided on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disorder, or prescribing any medication. The Preeclampsia Foundation presents all data as is, without any warranty of any kind, express or implied, and is not liable for its accuracy, for mistakes or omissions of any kind, nor for any loss or damage caused by a user's reliance on information obtained on the site. Professional opinions on this condition vary greatly. The Preeclampsia Foundation endorses no one course of treatment or "cure".
The Preeclampsia Foundation does not necessarily endorse any research or news found in this forum, we just want to share what is out there. Please use your own discretion to evaluate any information you find here.
1 post • Page 1 of 1
Users browsing this forum: No registered users and 2 guests