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Male sex bias in placental dysfunction

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Male sex bias in placental dysfunction

Postby caryn » Mon Mar 19, 2012 09:43 am

by caryn (10111 Posts), Mon Mar 19, 2012 09:43 am

In families with the absence of maternal chronic hypertension (cHTN; n = 70), the index case was 5.9 (95% CI 2.28-16.15; P <0.001) times more likely to be male and most (12/14) affected sibs of male index cases were male, while female index cases had no affected sibs. Our results confirm a male fetal sex preponderance in SPD. In a subgroup analysis of families without cHTN, a significant male bias was found to extend to sibs of index cases.

http://www.ncbi.nlm.nih.gov/pubmed/22407866

This is one that doesn't apply to me, because maternal family history of hypertension was excluded from the sample population. It says the rate of SPD - severe placental dysfunction - is way higher if you're carrying a boy.
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DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
DD Bridget born by C-section after water broke at 39 weeks after a healthy pregnancy
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Re: Male sex bias in placental dysfunction

Postby alviarin » Mon Mar 19, 2012 02:15 pm

by alviarin (1635 Posts), Mon Mar 19, 2012 02:15 pm

Interesting. Don't male babies tend to be bigger? I wonder if that could be a factor.

Though this doesn't really apply to me either since I'm a chronic hypertensive.
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(severe pre-e at 38 weeks & "mild" pre-e at 37 weeks)
& baby Annabelle
(chronic HTN & GD, superimposed pre-e @34 weeks, induction @37 weeks)
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