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Blood Pressure Change in Normotensive, Gestational Hypertens

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Blood Pressure Change in Normotensive, Gestational Hypertens

Postby caryn » Fri Apr 27, 2012 10:22 am

by caryn (10124 Posts), Fri Apr 27, 2012 10:22 am

Our findings indicate notable patterns of BP change that distinguish women with essential hypertension, gestational hypertension, and preeclampsia from each other and from normotensive women, even from early pregnancy. These distinct patterns may be useful for identifying women at risk of developing a hypertensive disorder later in pregnancy.

http://www.ncbi.nlm.nih.gov/pubmed/22526257

Math FTW! If we sort women into groups after the fact and look at their bp readings during pregnancy, there's a clear difference between the groups. Blood pressure readings from women in the set of normotensive pregnancies make one distinctive curve, chronics another, women with gestational hypertension another, and women with preeclampsia another. (Question: what do superimposed preeclamptics look like?)

So. If those curves are robust - if they hold up in further testing - then they can start mapping our pressure readings against "standard curves", and see which curve we're tracking the most closely. That could give us a much earlier diagnosis, and move us to the set of women who are high-risk for complications even before the complications develop. Yay!
Science! The articles you don't want to miss:
The Preeclampsia Puzzle (New Yorker) and Silent Struggle: A New Theory of Pregnancy (New York Times)
Looking for recent articles and studies? Lectures from researchers?
A chance to participate in research? For us on Facebook or Twitter?

Caryn, @carynjrogers, who is not a doctor and who talks about science stuff *way* too much
DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
DD Bridget born by C-section after water broke at 39 weeks after a healthy pregnancy
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caryn
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Re: Blood Pressure Change in Normotensive, Gestational Hyper

Postby LauraBeck12 » Sun Apr 29, 2012 04:21 pm

by LauraBeck12 (41 Posts), Sun Apr 29, 2012 04:21 pm

Did you see this? i thought if any one could break it down into human terms it would be you! <3 :

http://online.wsj.com/article/SB1000142 ... od=mostpop

http://hyper.ahajournals.org/content/ea ... 0.abstract
Laura Beck, mother to Our most cherished Love - Our son- 8/1/11- 8/4/11
severe swelling and increased blood pressure started between 20-22 weeks. (ignored by medical professionals)
was finally clinically diagnosed with severe pre-e at 27 weeks.
spent 2 weeks in hospital.
He was born at 29 weeks, at exactly 2lbs. classical incision c-section.
He lived for 3 days in the NICU , autopsy said "lung failure" was cause of death.

http://clercbaby.blogspot.com/
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Re: Blood Pressure Change in Normotensive, Gestational Hyper

Postby caryn » Sun Apr 29, 2012 05:40 pm

by caryn (10124 Posts), Sun Apr 29, 2012 05:40 pm

Yes - and I'm working on it, but epigenetics is tricky to explain in English. One of these days...
Science! The articles you don't want to miss:
The Preeclampsia Puzzle (New Yorker) and Silent Struggle: A New Theory of Pregnancy (New York Times)
Looking for recent articles and studies? Lectures from researchers?
A chance to participate in research? For us on Facebook or Twitter?

Caryn, @carynjrogers, who is not a doctor and who talks about science stuff *way* too much
DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
DD Bridget born by C-section after water broke at 39 weeks after a healthy pregnancy
User avatar
caryn
Forum Moderator
 
Posts: 10124
Joined: Fri Jun 25, 2004 06:36 am


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