by caryn (10131 Posts), Wed May 02, 2012 11:04 pm
This confirms our current understanding - which is important, because if it didn't we'd know we were on the wrong track! - that the placenta is producing the signalling that doesn't have that effect in the mother's body.
That could be because the placenta is sending the wrong signals. That could be because the mother's body isn't receiving them properly. That could be a combination of the two. Most genetic analyses that I've seen think it's both, most of the time, because of the way the inheritance patterns are working, with a stronger influence from maternal predisposition but a substantial parental contribution as well.