PPCM very well could be a "two-hit" process. Underlying genetic pre-disposition, whether a mutation on chromosone 12 http://intermountainhealthcare.org/hospitals/imed/about/news/Pages/home.aspx?NewsID=814
or a deficiency in PGC1-alpha like the knockout mice in the above study making some women overly sensitive to high sFLT1 levels. Which are even more elevated during pre-e pregnancies.
I still wonder if some of the long-term cardiovascular risks associated with pre-e could also be linked to hypothyroidism. Since sFLT1 also mucks with your thyroid gland and even subclinical hypothyroidism has been linked to increase in cardiovascular risk factors including high LDL cholesterol, high triglycerides, impaired myocardial contractility, diastolic dysfunction, and atherosclerosis.