Outcomes after first preg. w/sPE + deliv. before 34 weeks

[caryn]

Trophoblast is *weird* so no one is really sure. It is difficult to research because it's adapted for an environment that's difficult to recreate in a lab (inside a uterus, in the lining, which is mostly natural killer immune cells from another individual) and we can't really go looking during a pregnancy. I've seen some studies showing persistent remodeling effects up to seven years postpartum and others (like this one) that suggest that the majority of the remodeling is gone by 2 years postpartum.

I wonder if some trophoblast are carrying genes that mean they persist longer, or their remodeling effects persist longer. I would like to know!

[kaxy]

So interesting. I conceived my daughter when I was around 16ish months postpartum, and had PE with both kids. I'm now expecting my 3rd, conceived when my daughter was 25m. I hope it'll improve my outcome somewhat! I've gotta have something positive here

[luizaiulia]

jean » Lost my son also at 36 weeks due to PE, 10 days ago. My hart is broken. What is LDA? >>You wrote :


{Our second son was born at 39 weeks gestation in Nov of 2011. No HELLP or pre-e! Took LDA starting at week 12 and went off of it at week 38!}

[caryn]

Welcome. I'm so sorry to hear that you lost your son to this brutal disease.

LDA is low-dose aspirin. There are some meta-analyses of research data that suggest it might lower risk slightly; there are some trials that suggest that it does not, except maybe in a small subset of women who could not be identified from the studies. In any case it does not harm (or at least no harm showed up in the very large trials that were conducted.)