Pregnancy Induces Persistent Changes in Vascular Compliance

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caryn
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Pregnancy Induces Persistent Changes in Vascular Compliance

Postby caryn » Fri Jan 16, 2015 06:26 pm

"Our observations of decreased mean arterial pressure and reduced arterial stiffness following pregnancy suggest a significant favorable effect of pregnancy on maternal cardiovascular remodeling. These findings may represent a mechanism by which preeclampsia risk is reduced in subsequent pregnancies."

http://www.ncbi.nlm.nih.gov/pubmed/25576820

So they compared biomarkers in women before and after a first pregnancy, and it turns out that pregnancy just generally loosens your arteries and lowers your blood pressure. (RELAX ALL THE THINGS.) That's probably why - even if you had preeclampsia - your later pregnancies are likely to be easier, with any reoccurrence being later and milder. Of course, this isn't true for everyone, but in the general population of women who've had preeclampsia in a first pregnancy, about 15% get GH/PE/HELLP in a subsequent pregnancy and usually it's less of a crisis than the last time was.

On another note I bet this is why women have better cardiac outcomes than men...
Science! The articles you don't want to miss:
The Preeclampsia Puzzle (New Yorker) and Silent Struggle: A New Theory of Pregnancy (New York Times)
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Caryn, @carynjrogers, who is not a doctor and who talks about science stuff *way* too much
DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
DD Bridget born by C-section after water broke at 39 weeks after a healthy pregnancy

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