Placental Foxp3 expression in patients with preeclampsia

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caryn
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Placental Foxp3 expression in patients with preeclampsia

Postby caryn » Sat Jan 24, 2015 09:25 pm

"The expression level of Foxp3 in the placental tissue of preeclampsia patients is significantly lower than that in normal pregnant women, suggesting that lowered Foxp3 expression decreases the immunosuppressive function and causes imbalance of immune tolerance between maternal-fetal to induce preeclampsia."

http://www.ncbi.nlm.nih.gov/pubmed/25613614

Yet another bit of data saying it isn't something you did wrong - it's that your placenta's genetic immune signaling isn't proceeding normally in the pregnancies that develop preeclampsia. Here's the Wikipedia on Foxp3: http://en.wikipedia.org/wiki/FOXP3
Science! The articles you don't want to miss:
The Preeclampsia Puzzle (New Yorker) and Silent Struggle: A New Theory of Pregnancy (New York Times)
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Caryn, @carynjrogers, who is not a doctor and who talks about science stuff *way* too much
DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
DD Bridget born by C-section after water broke at 39 weeks after a healthy pregnancy

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