by caryn (10146 Posts), Wed Nov 04, 2009 12:13 am
The mean plasma concentrations of HbF, HbA, protein carbonyl groups, membrane peroxidation capacity and alpha(1)-microglobulin were significantly increased in preeclamptic women. The levels of total plasma Hb correlated strongly with the systolic blood pressure. The plasma haptoglobin concentrations of women with preeclampsia were significantly depressed. Increased amounts of alpha(1)-microglobulin-mRNA and protein were found in placenta from preeclamptic women and the levels of plasma and placenta alpha(1)-microglobulin correlated to plasma Hb-concentrations...
Hmmm. That might have something to do with the rarity of anemia diagnoses among preeclamptics. We've got significantly higher bloodstream levels not just of maternal hemoglobin, but fetal as well -- and also higher levels of the oxidative markers associated with hemoglobin.
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