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Preeclampsia and risk of subsequent diabetes

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Preeclampsia and risk of subsequent diabetes

Postby caryn » Mon Oct 26, 2009 07:16 pm

by caryn (10111 Posts), Mon Oct 26, 2009 07:16 pm

Preeclampsia was associated with a higher risk of diabetes adjusting for age, primigravidity, and gestational diabetes (hazard ratio, HR 1.82, 95%CI 1.26, 2.62) and in women without gestational diabetes (n = 30,109; HR 1.86, 95%CI 1.22, 2.84).

http://www.ncbi.nlm.nih.gov/pubmed/19843005

Great. Even if you didn't get GD, you're at almost double the risk of developing diabetes. In fact, there's hardly any difference between the two groups.

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Re : Preeclampsia and risk of subsequent diabetes

Postby sonja » Mon Oct 26, 2009 08:12 pm

by sonja (5658 Posts), Mon Oct 26, 2009 08:12 pm

I don't even know what to say!
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Re : Preeclampsia and risk of subsequent diabetes

Postby missgamecock » Mon Oct 26, 2009 08:32 pm

by missgamecock (6064 Posts), Mon Oct 26, 2009 08:32 pm

That does NOT make me happy!!! Not having GD was the one thing that I passed in pregnancy!
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Re : Preeclampsia and risk of subsequent diabetes

Postby blythe » Mon Oct 26, 2009 08:41 pm

by blythe (3060 Posts), Mon Oct 26, 2009 08:41 pm

Did they control for BMI? Did they speculate on the correlation?

I'm just not pleased to hear this and want an alternative explanation! ;-b
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Re : Preeclampsia and risk of subsequent diabetes

Postby brooklynsmom » Mon Oct 26, 2009 09:30 pm

by brooklynsmom (627 Posts), Mon Oct 26, 2009 09:30 pm

Well, since I had one in each pregnancy, I guess I am really in trouble, then, hey?
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Re : Preeclampsia and risk of subsequent diabetes

Postby southerngirl108 » Mon Oct 26, 2009 10:58 pm

by southerngirl108 (44 Posts), Mon Oct 26, 2009 10:58 pm

Great.....
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Re : Preeclampsia and risk of subsequent diabetes

Postby for faith » Tue Oct 27, 2009 07:05 pm

by for faith (1749 Posts), Tue Oct 27, 2009 07:05 pm

Wow, had never heard this before......have Type I and Type II in my family (but no GD for me).....guess I am destined for it.....
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Re : Preeclampsia and risk of subsequent diabetes

Postby angelr » Thu Apr 22, 2010 10:06 pm

by angelr (18 Posts), Thu Apr 22, 2010 10:06 pm

I had GD both pregnancies, PE both times. The first time (3 y ago) my blood glucoses went back to normal after delivery. This time, not so lucky. I have Type 2 DM now but still diet controlled (I am amazed how few carbs one should really be eating!) My BMI is 23, I am very active and have never been overweight. No one in my family has or had DM on either side. So I believe I am the perfect case of this phenomenon :o) Not happy about it but I can manage it.
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Re : Preeclampsia and risk of subsequent diabetes

Postby rebeccac » Thu Apr 22, 2010 11:22 pm

by rebeccac (761 Posts), Thu Apr 22, 2010 11:22 pm

So on the flip side, diabetes makes you more prone to preeclampsia (I already had (have) it)?
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Re : Preeclampsia and risk of subsequent diabetes

Postby angelr » Fri Apr 23, 2010 09:08 am

by angelr (18 Posts), Fri Apr 23, 2010 09:08 am

Yes, diabetes is one of the known risk factors for PE. Elevated blood glucose causes endothelial damage(lining of the blood vessels)which is why diabetics are prone to micro and macro-vascular damage. The maternal manifestation of preeclampsia is widespread endothelial derangement so I suppose anything that predisposes you to this damage can only work hand in hand to make things worse on both ends :o(
But on a positive note I know someone who is a very, very "brittle" diabetic who delivered a healthy baby at age 42 with nary a sign of PE...
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