by caryn (10159 Posts), Mon Dec 21, 2009 10:19 am
...significant differences in angiogenic factors and adiponectin were found between normal and overweight women only in late-onset pre-eclampsia... These data suggest that there are different profiles of angiogenic factors and adipocytokines between women who develop early- and late-onset pre-eclampsia...
So maybe they'll be able to develop some sort of reliable test that says whether or not you'll get PE earlier or later. Women who develop it earlier have higher levels of some specific chemicals.
It also looks like there's a difference in the chemical profiles between overweight women who develop PE and regular-weight women who develop PE. That probably means that there's a difference in what it is that tips individuals over the threshold. (Anne's cup-of-water analogy works here: each of us has different underlying predispositions to the disease, and preeclampsia is when the cup runneth over...)
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