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New Article on Urine test early in pregnancy can predict PE

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New Article on Urine test early in pregnancy can predict PE

Postby miamibunnie » Sun Dec 12, 2010 12:20 am

by miamibunnie (510 Posts), Sun Dec 12, 2010 12:20 am

I previously posted an article but I dont think the ladies in the forum were able to connect to the link....but I copied pasted it See below....


December 1, 2010 (Denver, Colorado) — A simple measurement of key proteins in spot urine samples can detect preeclampsia in women during the early stages of pregnancy, according to research presented here at Renal Week 2010: American Society of Nephrology 43rd Annual Meeting.

Researchers in the United Kingdom report that an analysis of urine samples obtained before 20 weeks of gestation from 145 pregnant women who either did or did not develop preeclampsia allowed them to identify 5 protein peaks that predicted preeclampsia with 92% accuracy.

The clinical signs of preeclampsia typically do not appear until later in pregnancy, but the researchers theorized that because abnormal placentation or placental insufficiency is central to the pathogenesis of preeclampsia, and placentation is complete by 18 weeks of gestation, changes in the urinary protein profile early in pregnancy might predict the development of the disease...


Renal Week 2010: American Society of Nephrology 43rd Annual Meeting. Abstract FC223. Presented November 19, 2010.

(Mod note: so sorry to edit this, but we can't quote the whole thing because of copyright issues. Have left in the citation information so that you can find the scientific paper and maybe miamibunnie will repost the link.)
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Re: New Article on Urine test early in pregnancy can predict

Postby jean » Mon Dec 13, 2010 08:10 am

by jean (675 Posts), Mon Dec 13, 2010 08:10 am

So my question is when will it be available in the US?
Our first son was born and passed in Feb of 2010. Born at 29 weeks due to HELLP and passed due to NEC. We miss him every day. :~(

Our second son was born at 39 weeks gestation in Nov of 2011. No HELLP or pre-e! Took LDA starting at week 12 and went off of it at week 38!

http://findingtherainbowconnection.blogspot.com/
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Re: New Article on Urine test early in pregnancy can predict

Postby miamibunnie » Tue Dec 14, 2010 09:19 pm

by miamibunnie (510 Posts), Tue Dec 14, 2010 09:19 pm

I dont know but it mentions that it will be avaiable soon. That means maybe in a few years...or who knows.
Lisette 37 Hubby 37
Lisette 36 / Luis 36
1996 25 weeker due to Eclampsia with seizures daughter alive today 15 yrs old " Julyzah Caridad"
2010 23 weeker due to severe preeclampsia my angel left us

2011/27/July we beat preeclampsia and made it to 36.5 weeks 6lbs 1oz baby girl "Kendall Lauren " pe-free just bp started acting up.
Thanks to God, my doctor, Lovenox and Lda.
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Re: New Article on Urine test early in pregnancy can predict

Postby angieb » Tue Dec 14, 2010 09:33 pm

by angieb (1192 Posts), Tue Dec 14, 2010 09:33 pm

Interesting! Thanks for sharing!
Me (29) DH (30)
#1-Olivia Caetlyn-9-28-09-9-28-09, 23+2 wks, emergency classic c-section, class I HELLP, IUGR
#2- Lucas Oliver (rainbow baby)- April 2011, 36+2 wks, HELLP and pre-e free! (lovenox and LDA pregnancy)
#3-Matthew, late October 2012...mostly normal, 37 wks, (lovenox and LDA again)
My blog: http://www.butterflies-and-rainbows.blogspot.com/
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Re: New Article on Urine test early in pregnancy can predict

Postby caryn » Thu Dec 16, 2010 11:44 pm

by caryn (10124 Posts), Thu Dec 16, 2010 11:44 pm

This test is at least five years out, if someone throws funding behind it. Urine tests are often cheaper so it definitely has potential.

A blood test for sFlt-1 and sEng and their rate of change over time should be available shortly in the US and is already available in Europe.
Science! The articles you don't want to miss:
The Preeclampsia Puzzle (New Yorker) and Silent Struggle: A New Theory of Pregnancy (New York Times)
Looking for recent articles and studies? Lectures from researchers?
A chance to participate in research? For us on Facebook or Twitter?

Caryn, @carynjrogers, who is not a doctor and who talks about science stuff *way* too much
DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
DD Bridget born by C-section after water broke at 39 weeks after a healthy pregnancy
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