Originally posted by riehlism
The first link Lisette provided does site:
Prevention of Preeclampsia and Intrauterine Growth Restriction With Aspirin Started in Early Pregnancy: A Meta-Analysis
Obstet Gynecol 2010;116:402-414.
So it looks like the most recent issue of Obstetrics and Gynecology Journal. If you were trying to find the actual literature you can find this on PubMed.
The meta-analysis is the strongest type of research in the heirarchy of the types of research articles. The gold standard in research is a randomized controlled trial (RCT). A meta-analysis analyzes multiple RCTs. So it looks like this study analyzed the results for 34 RCTs, which is why the population is so high (11,000+ women). This is a pretty strong article.
Please remember not every research article printed in a journal is a well done article. Meaning, results of a research is only as strong as the design of the research. If the design is weak, the results pretty much mean nothing. Typically, it's people who are involved in the ins and outs of the field that can fully determine the strength of the article, which therefore strengthens the result.
In any case, fantastic find Lisette!
For the Moderators: is there any way someone can post information to provide the members with the tools to figure out how to understand the parts of a journal article? People are used to accepting that if something is printed in a medical journal, it's as good as the Gospel. It seems that people on this site are truly trying to understand the science behind what's happening and want to be on top of the most current research. Just my opinion, but I think giving members the tools to be able to pick out good articles might be empowering. (Eg: discussing study designs and why one study might be stronger than another, basic statistical analysis, etc).
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