PE immune maladaptation hypothesis still standing?

The Preeclampsia Foundation does not necessarily endorse any research or news found in this forum, we just want to share what is out there. Please use your own discretion to evaluate any information you find here.
blythe
Registered User
Posts: 3059
Joined: Sun Mar 21, 2004 10:24 am

Re : PE immune maladaptation hypothesis still standing?

Postby blythe » Tue May 15, 2007 09:15 am

Dang. That's me - BMI 25 before both pregnancies, age 31 and 34 when the boys were born, and BP started going up at 36 weeks (but not diagnostic with proteinuria at 37 and 36 4/7 inductions - just cautious doctors who were sure the proteinuria was on it's way so we induced!). *Very* interesting (to me) because it feels like they're writing about me [;)].

User avatar
caryn
Forum Moderator
Posts: 10203
Joined: Fri Jun 25, 2004 06:36 am

PE immune maladaptation hypothesis still standing?

Postby caryn » Sun May 13, 2007 05:10 am

"One of the explanations for contradictory findings might be that the type of pre-eclampsia seen by obstetricians in developed countries mostly involves 30 and more years old, mildly obese pregnant women having near-term pre-eclampsia..."

http://www.ncbi.nlm.nih.gov/entrez/quer ... med_docsum

Our Experts have been saying this for a while now. We absolutely have to break these populations down phenotypically in order to make further progress. It's why they refer to it as the 'preeclampsia syndrome'; we are likely to be looking at a similar cluster of symptoms with multiple different causes. Some women probably have shallowly implanted placentas, some women have a higher inflammation baseline, some women have an inherited thrombophilia, etc., and until we look at populations of women with only certain risk factors and see what it is that's going on with those cases only, we can't really say much more about why PE happened to them.

Information provided on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disorder, or prescribing any medication. The Preeclampsia Foundation presents all data as is, without any warranty of any kind, express or implied, and is not liable for its accuracy, for mistakes or omissions of any kind, nor for any loss or damage caused by a user's reliance on information obtained on the site. Professional opinions on this condition vary greatly. The Preeclampsia Foundation endorses no one course of treatment or "cure".


Return to “Announcements and Preeclampsia in the News”

Who is online

Users browsing this forum: No registered users and 0 guests