Magnesium Sulfate

Are you part of the NICU club? Do you have a child who is still struggling with the effects of being born too soon from preeclampsia? Share your concerns and stories here among parents who have been there.
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hannahsmom
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Re : Magnesium Sulfate

Postby hannahsmom » Thu Sep 06, 2007 12:54 am

I was on Mag for 24 hours prior to delivery but it had to be stopped because they thought the mag was causing the pulmonary edema (fluid around my heart) so once they stopped the mag they took me in for surgery to deliver Hannah - they were afraid I was going to have a stroke or seizure or heart attack. All I remember is that in the delivery room my BP was 200 and something over 200 and something [xx(]I received lasix during this time and I am pretty sure I went back on the mag after the c-section. That was my experience with mag - it's icky stuff, but during my ambulance ride from one hospital to the other, the paramedic said if I wasn't on mag, I would be in big trouble.

kara
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Re : Magnesium Sulfate

Postby kara » Mon Sep 03, 2007 10:27 pm

Zoe526, The mag is to protect you from having a seizure or stroke. It can affect the baby and cause them to be tired, sluggish, etc, but they are minor side effects for a drug that may save your life. It's very easy for the doctors to overdose on Mag. I was overdosed too. They want to make sure to give you enough to keep you from having seizures and strokes, but sometimes the body does really well with it and then the next minutes it's had too much. It's usually easy for them to monitor and then take you off of it for awhile. However, you will get the mag symptoms of nausea and hot flashes almost immediatley....that pretty much happens to everyone. You don't have to be toxed out on it to have those reactions. And PLEASE see a perinatologist or MFM-high risk OB BEOFRE you get pregnant. They will often times run tests to see if there are any underlying disorders that are contributing to you getting PE. If there are, and they can treat them, then they'll treat you and you might have a greater chance of having a boring pregnancy. But you should have that chat with the doc about your records and about testing before you ttc again, if at all possible. It's called a prec-conception appointment.

To get your records, call your doctors office and the hospital where you delivered and ask them how you can request copies of your records. There is usually a form to fill out and sign, and often a fee to have them copied and sent to you. I ordered mine and am very glad I did....I learned a lot from them, and so did my new doctors. Your doctor can also order them for their records, and you won't be charged...but it's good to have your own copy so you can read them and ask lots of questions.

Good luck!

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Re : Magnesium Sulfate

Postby onesock » Mon Sep 03, 2007 09:06 pm

Mag is nasty stuff, there is no doubt about that. It does make you feel terrible, but it smooths out muscle tissue and helps the veins stop contracting, thus helping blood flow. I thought that when they gave it to me, they were giving me poison, but it protected me from seizures and stroke, so I will be grateful for that nasty stuff forever.

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annegarrett
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Re : Magnesium Sulfate

Postby annegarrett » Mon Sep 03, 2007 07:46 pm

I agree with Catherine's advice--we're not doctors here so anything we suggest is all just speculation (and even if we were doctors, we're not your doctor). I'd get your records, make an appointment with a specialist in your area (happy to help you identify someone, just email us) and ask for some preconceptual advice. :) Best wishes!!

zoe526
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Re : Magnesium Sulfate

Postby zoe526 » Mon Sep 03, 2007 07:41 pm

How do I get a copy of my hopsitalization records?
You it sounds awefully funny but far too many people even my cousin a lab technician have said I may have been given too much. Icalled my Dr. and left a message as to what I 'd like to discuss with him. He's really good and I think if he was there things would have been better. So we are going to work together on this one when it happens. I hope I have a boring noneventful next pregnancy.

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catherine
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Re : Magnesium Sulfate

Postby catherine » Mon Sep 03, 2007 06:29 pm

Can I suggest that you request copies of your hospitalization records? This will give you the best information regarding your previous preeclampsia experience. That way you would be in a position to bring actual data to your next OB or peri. HELLP is usually diagnosed from bloodwork values. HELLP is essentially a variant of severe preeclampsia and one that includes a blood clotting component. In this case, the destruction of platelets triggered by the disease can greatly reduce your ability to clot. If, on the other hand, your problems were caused by MgSO4, either toxicity because you were given to much, or allergy, this can be evaluated before you become pregnant.

deerhart
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Re : Magnesium Sulfate

Postby deerhart » Mon Sep 03, 2007 12:46 am

Actually mag can have the same side effects on the baby as it does on the mom. When Alex was born he was charcoal blue (no cord around his neck and breathing was fine) and lacked motor activity, which were side effects from the mag. Heck, he didn't cry for several days (again side effect of the mag).

As for an allergic reaction, they are extremely rare. In fact some people will refuse to believe that sulfate allergies exist (mostly because they don't understand how allergies work) as it naturally occurs in the body. Not only did I have my common allergy problems, but I also broke out in hives, had burns (which may had started as hives and just continued to get worse as the metal and mag mixed), and the effects lasted from 5-10 days after the mag was stopped (which is normal for me to have a delayed reaction time to an allergen of up to 3 days).

As for no one mentioning HELLP to you, that is not all that uncommon. Heck lots of times docs will note something in our records and never tell us. I was once diagnosed with mono (despite have 3 negative mono tests), never told, and continued exercising for 1-2 hours every day. I found out 3 years later when another doc in the clinic said o I see you had mono 3 years ago..

As for side effects, 99% of the time your not going to get a choice of whether to give it or not. They are going to give it to you regardless because its the only thing they can do. That being said, if you have a really hard time with it, that is something you and the doc may want to take into consideration when its time to delvier the next time around. This was one of the reasons my 2nd child was induced quickly at 36 weeks instead of waiting 1-2 more weeks (when he probably would have come on his own) as my condition was just starting to really deteriorate, I was deteriorating much faster then last time, and inducing NOW would decrease the chances of having to turn to mag.

As for mag causing you not to clot, actually research indicates that mag sulfate is very important in the clotting cascade an will actually help your blood to clot. Also magnesium sulfate and magnesium citrate are both used to treat liver disease, cleanse the liver, and are used during liver transplants. I am not sure that hte liver filters mag, such that having it would cause any problems (unlike alcohol which is filtered through the liver and does cause damage).

season
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Re : Magnesium Sulfate

Postby season » Mon Sep 03, 2007 04:28 am

I think when it comes to needing mag, the doctors aren't real focussed on discussing it with the mom. It is seen as necessary to prevent much more serious problems (seizure or stroke) than any of the possible side effects.


It is best to dicuss any concerns with your doctor, esp before another pregnancy so that you can be as informed as possible.

zoe526
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Re : Magnesium Sulfate

Postby zoe526 » Sun Sep 02, 2007 11:07 pm

Wow thanks for all the advice...had I know this 2 years ago......... Well anyway I am hoping to get pregnant again soon...and hoping for a noneventful pregnancy...the more boring the better. That being aaid my doctor and I will have a long chat when I have to start going. I really did not like that I wasn't counciled more of the possible side effects when I was in the hospital..I think it should be discussed in full. I do think something went wrong and they had no idea of what the heck was going on but I really do think that I will just take my chances with the NICU. I was worried but after I finally got to see her I just knew she would be ok. They are angels those nurses and NICU dr's.

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caryn
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Re : Magnesium Sulfate

Postby caryn » Sun Sep 02, 2007 03:23 am

A significant subfraction -- something like 30% -- of severe preeclampsia patients develop what they call "superimposed" HELLP, which is to say that it's preeclampsia that's gone on for too long for the mother's body to tolerate, often because they're trying to get the steroid shots in and have stabilized you with mag and IV bp meds and oxygen, and delayed delivery.

Mag sulfate is the only known drug which lowers the mother's risk of stroke and seizure. There are no alternatives yet, so declining it would mean running a significant risk.

IIRC in women with allergies to it, the strategy is usually to deliver early via c-section, before the mother has developed preeclampsia and to avoid the production of sFlt-1 during labor, with the tradeoff of a higher chance of prematurity and attendant complications. And, of course, a guaranteed c-section.

I'd discuss this with your care providers further.


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