CA-125 and CRP are elevated in preeclampsia

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CA-125 and CRP are elevated in preeclampsia

Postby caryn » Sat May 16, 2009 01:50 am

...CRP and CA-125 parameters were significantly higher in the study group (p < 0.001), and were significantly higher in severe preeclampsia and eclampsia groups than in mild preeclampsia (p < 0.001). Significant correlations were found between CRP/MAP, CRP/albumin, CA-125/MAP and CA-125/albumin (p < 0.001)...

Oooh. CRP is C-Reactive Protein, which is a marker of inflammation, which is a response of our innate immune system. So it's coming from the part that goes ATTACK! for any foreign invasion whatsoever, the older part of the immune system. But CA-125 is a cancer tumor antigen, which means it's a response of our *adaptive* immune system, the newer part that recognizes invaders and responds by generating antibodies.

So this is weird. Then again, placentas are a lot like tumors.

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