New Here- lots of questions

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alviarin
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Location: Texas

Re : New Here- lots of questions

Postby alviarin » Tue May 06, 2008 11:59 am

Hi Sheri,
Welcome to the forums.

I'm also on thyroid medication, though I haven't been officially diagnosed with Hashimoto's yet. It definitely runs in the family, though I'm the only hypo lady to also get pre-eclampsia (lucky me!).

Hypo- and hyper- thyroidism are both risk factors for pre-eclampsia. http://www.preeclampsia.org/forum/viewtopic.php?t=18419

Normalization of thyroid values pre-pregnancy seems to lower the incidence of PE, but one study found that even among pregnant women with treated hypothyroidism, their incidence of hypertension and pre-eclampsia was higher than that of the control group (2.3% vs. 1.2% and 4.3% vs. 2.6%)
http://www.ncbi.nlm.nih.gov/entrez/quer ... t=Abstract

There seems to be a link between Hashi's and infertility, even with sub-clinical hypothyroidism. Most people without thyroid problems have a TSH between 1-2 mIU/L, and "In the future, it is likely that the upper limit of the serum TSH euthyroid reference range will be reduced to 2.5 mIU/L because >95% of rigorously screened normal euthyroid volunteers have serum TSH values between 0.4 and 2.5 mIU/L."
http://www.aacc.org/members/nacb/LMPG/O ... sePDF.aspx
Personally I didn't conceive until my TSH was below 2 mIU/L on meds, and my free T3 and free T4 were above mid-range.

You probably already know this, but more frequent thyroid testing is necessary during pregnancy because thyroid requirements increase. Most (but not all) hypothyroid women require their thyroid meds upped roughly 30-50% during pregnancy. http://thyroid.about.com/od/hormonepreg ... yguide.htm

If you want a second opinion on the MTHFR/blood thinners you could consult a maternal fetal medicine specialist. I only have one MTHFR mutation, but the high risk ob I consulted said I could try baby aspirin on top of taking folic acid (though not as much as her patients with two mutations), even though my homocysteine levels are normal.

sonja
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Re : New Here- lots of questions

Postby sonja » Mon May 05, 2008 04:03 pm

Hi Sheri - wow, you have a lot that you are dealing with. We have some gals here that speak your language - hopefully they will pop on here and give you some of their personal stories. Also, there is an underlying disorders forum here that you might find some more info on - I know that we have other members with Hashimoto's as well at Homo MTHFR.

Take care and welcome to the website.

sheri-ct
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Joined: Mon May 05, 2008 11:47 am

New Here- lots of questions

Postby sheri-ct » Mon May 05, 2008 03:17 pm

Hi,

After 4 years of infertility, I finally conceived twins in 2007.  The pregnancy was going really well until 31 weeks.  I started to bleed and my bp started to go up.  I was given steroid shots and kept in the hospital overnight.  I was then sent home on bed rest only to return back to L&D 5 days later with a migraine and severe neck/back pain.  My bp was 170/110.  It was determined that I had severe pre-e and was delivered via c-section immediately at 32 weeks.  Both babies were pretty small and my DS's placenta had several clots.  Both babies were vent dependant and my DS was not responding to the traditional vent.  He needed to be transferred to another NICU and put on an oscillating ventilator.  Thankfully, they are both doing well after staying in the NICU for 6 weeks.

We are planing on doing a FET next month.  I have recently been diagnosed with Hashimoto's.  I always had high ATAs, but my TSH was always in the normal range.  I am now on Synthryoid.  I also recently discovered that I am Homo MTHFR C677T and Hetero PAI-I.  I called my RE and he checked my homocysteine level, which was 7.  He said that no treatment was necessary.  Uncomfortable with that, I called my OB.  She has started me on Folgard once a day and LDA.  She is not sure if the Lovenox is necessary, so she sending my to MFM for a consult, but I am not sure if I can get in before my FET.  

Is there anything else I should be doing?  My OB said that the recent studies say that the Lovenox is not helping?  Is that true?  Where can I find some information to share with her that suggests otherwise?  If I made it to 32 weeks with twins, does that increase my chances of making it to 37 weeks with a singleton?

Any advice would be greatly appreciated.  This diagnosis is fairly new and I am so confused and scared.  Thanks.

Sheri


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