2011 Vision Grant recipient Dr. Nihar Nayak has published his work with sFLT-1, a protein related to blood vessel development in the early part of pregnancy and strongly implicated in the vascular dysfunction associated with preeclampsia. Published in the well-respected Journal of Clinical Investigation, Nayak's team discovers that another pregnancy related substance, VEGF, is responsible for triggering the overproduction of the much-discussed sFLT-1. However, the findings show that sFlt1 can actually help to protect the fetus by "sequestering" excess VEGF, even though this is dangerous for the mother.
You can read about his original Vision Grant research on our website.
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Frequently asked questions about the Preeclampsia Registry, a patient-driven registry and biobank.
The Preeclampsia Foundation offers research funding, study recruitment, and other patient engagement services to researchers.
We provide research grant funding to advance progress towards detection, prevention, or treatment of preeclampsia, HELLP syndrome, and other hypertensive disorders of pregnancy.
While the foundations of preeclampsia are believed to develop in the early stages of pregnancy, the current screening process occurs at 20 weeks, nearly half way through the second trimester. When cli...
Research suggests that preeclampsia may develop in a two-stage process. The first stage involves challenges to the way that the placenta implants and grows. In a normal pregnancy, a type of placental...
The risk of developing hypertension and cardiovascular disease (CVD) significantly increases for patients who experience gestational hypertension, preeclampsia, or other hypertensive disorders of preg...
Cerebral complications from preeclampsia and eclampsia are a major cause of maternal mortality and long-term neurological impact. Understanding pathophysiology (changes in how the body works as a resu...
The Preeclampsia Foundation is seeking Letters of Intent for the Peter Joseph Pappas Research Grants funding program, designed to accelerate preeclampsia research. The ultimate goal of this grant prog...