2011 Vision Grant recipient Dr. Nihar Nayak has published his work with sFLT-1, a protein related to blood vessel development in the early part of pregnancy and strongly implicated in the vascular dysfunction associated with preeclampsia. Published in the well-respected Journal of Clinical Investigation, Nayak's team discovers that another pregnancy related substance, VEGF, is responsible for triggering the overproduction of the much-discussed sFLT-1. However, the findings show that sFlt1 can actually help to protect the fetus by "sequestering" excess VEGF, even though this is dangerous for the mother.
You can read about his original Vision Grant research on our website.
Your story is needed to improve outcomes for moms like you. Add your voice to critical preeclampsia research to ensure that every story is heard.
Frequently asked questions about the Preeclampsia Registry, a patient-driven registry and biobank.
The Preeclampsia Foundation offers research funding, study recruitment, and other patient engagement services to researchers.
We provide research grant funding to advance progress towards detection, prevention, or treatment of preeclampsia, HELLP syndrome, and other hypertensive disorders of pregnancy.
The Preeclampsia Foundation is seeking Letters of Intent for the Peter Joseph Pappas Research Grants funding program, designed to accelerate preeclampsia research. The ultimate goal of this grant prog...
A new research study suggests that blood pressure changes during the first 20 weeks of pregnancy—called blood pressure trajectories—may give providers a peek at a woman’s risk of dev...
Preeclampsia is a major cause of maternal and fetal morbidity and mortality. Prompt and accurate diagnosis is necessary to prevent adverse outcomes. A study was completed to determine the accura...
Predicting preeclampsia has proven to be a challenge. Researchers have documented many differences in early pregnancy between those who eventually develop preeclampsia and those who do not. These incl...
The U.S. Preventive Services Task Force (USPSTF) and American College of Obstetricians and Gynecologists (ACOG) guidelines changed in 2021 to help prevent preeclampsia. Low-dose aspirin has been shown...