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We asked our Preeclampsia Registry participants to submit their own research questions. Check out the Ask an Expert Series providing answers to these questions. If you want to submit your research question, enroll today or login!
What do we know? Creating an effective understanding of nutrition and preeclampsia
March 23, 2023
What do we know? Creating an effective understanding of nutrition and preeclampsia

Researchers have found several maternal nutritional and dietary factors that may increase or decrease the risk of developing preeclampsia, though the association between the two is complex.

Could Vitamin B12 deficiency and preeclampsia/HELLP syndrome be related?
June 14, 2021
Could Vitamin B12 deficiency and preeclampsia/HELLP syndrome be related?

An association between low levels of B12 in the bloodstream during pregnancy and an increased risk for preeclampsia exists; however, research results suggest that low levels of B12 are associated with preeclampsia because of shared metabolic pathways...

Why doesn't aspirin work for some women?
June 16, 2020
Why doesn't aspirin work for some women?

Low dose aspirin is prescribed in pregnancy to prevent preeclampsia, but some women may experience a condition known as aspirin resistance, in which case aspirin treatment is not effective.

Progesterone injections and preeclampsia
March 09, 2020
Progesterone injections and preeclampsia

Is there a link between progesterone usage and preeclampsia? Science writer Caryn Rogers weighs in on what the research shows.

Is polycystic kidney disease related to preeclampsia or HELLP?
February 22, 2020
Is polycystic kidney disease related to preeclampsia or HELLP?

Women with polycystic kidney disease (PKD) are at higher risk of all forms of preeclampsia.

Is metformin protective?
November 01, 2019
Is metformin protective?

There are some reasons to think metformin, used differently from how it is used in polycystic ovarian syndrome (PCOS) or diabetes, might lower risk of preeclampsia, and other reasons to think it might not have much effect.

Celiac disease and preeclampsia
August 23, 2019
Celiac disease and preeclampsia

The largest meta-analysis of this question to date included almost 5 million women and found no differences in the rate of preeclampsia when women with celiac disease were compared to women without it.

What risk is added by Factor V Leiden?
August 07, 2019
What risk is added by Factor V Leiden?

The connection between Factor V Leiden deficiency and HELLP syndrome is unclear.

Do your Vitamin D levels prior to pregnancy affect your risk for preeclampsia?
July 25, 2019
Do your Vitamin D levels prior to pregnancy affect your risk for preeclampsia?

There is a known relationship between levels of vitamin D in the maternal bloodstream and preeclampsia. When pregnancy levels have been measured, women with higher levels develop preeclampsia less often than women with lower levels.

Thyroid antibodies and preeclampsia
July 25, 2019
Thyroid antibodies and preeclampsia

Researchers have wondered about the thyroid antibodies/preeclampsia relationship too, but the more it has been studied the less likely it seems. The idea, roughly, is that since thyroid disorders are known to raise risk of miscarriage and preterm bir...

Is there a connection between hyperemesis gravidarum and preeclampsia?
July 09, 2019
Is there a connection between hyperemesis gravidarum and preeclampsia?

Hyperemesis gravidarum (HG), is severe and persistent nausea and vomiting in pregnancy that, unlike morning sickness, can last until delivery. It is not well understood, but does seem to be related somehow to preeclampsia.

Does sleep apnea increase risk for preeclampsia?
June 13, 2019
Does sleep apnea increase risk for preeclampsia?

Women with sleep apnea are known to be at higher risk of chronic hypertension, which raises the risk for preeclampsia, and are at higher risk of preeclampsia, even if they are not chronic hypertensives.

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